Innovating Regenerative and Integrative Life Sciences

From Fundamental Biology to Translational Impact

Translational Focus in Cutaneous and Regenerative Biology

At the Advanced Centre for Regenerative Medicine and Stem Cell Research in Cutaneous Biology (AcREM-STEM), research is driven by the mission to translate fundamental biological discoveries into clinically and socially relevant solutions for skin, hair, ageing, and systemic health.

The Centre adopts a multidisciplinary and integrative approach, combining modern biomedical science with traditional knowledge systems and advanced model organisms

Thrust Areas of Research

Hair and Skin Regeneration

Decoding the Biology of Renewal

A major thrust of AcREM-STEM is understanding the cellular, molecular, and pathological mechanisms governing hair follicle cycling, skin homeostasis, wound healing, and regenerative failure. Research focuses on stem cell dynamics, tissue microenvironment, signalling pathways, and disease-associated alterations in cutaneous tissues to develop regenerative and therapeutic strategies.

Cutaneous Microbiome and Antimicrobial Research

Microbial Ecology for Skin Health

The Centre undertakes comprehensive profiling of skin and hair microbiomes and evaluates their role in health, disease, and therapeutic response. These studies are integrated with antimicrobial screening and efficacy assessments of natural and synthetic compounds to address infections, dysbiosis, and inflammatory skin disorders.

Healthy Ageing and Longevity Biology

Mechanisms of Lifespan and Tissue Resilience

AcREM-STEM explores the biology of ageing using alternative animal models and relevant human and animal cell lines. Research aims to identify molecular pathways that regulate longevity, stress resistance, metabolic balance, and tissue maintenance, contributing to strategies that promote healthy ageing and delay degenerative processes.

Nutraceuticals and Functional Foods

Science-Driven Wellness Solutions

The Centre actively engages in the development and biological validation of nutraceuticals and functional foods. Studies emphasize efficacy, safety, mechanistic understanding, and translational potential, supporting evidence-based formulation and product development.

Ayurveda Biology and Integrative Medicine

Bridging Tradition with Modern Science

A strong emphasis is placed on the scientific validation of Ayurvedic and traditional formulations. Using advanced cellular, molecular, and animal model systems, AcREM-STEM establishes experimental frameworks to generate evidence for safety, mechanism of action, and therapeutic potential of traditional remedies.

Research Highlights

  • Stem cell-based approaches for skin and hair regeneration
  • Microbiome-host interaction in cutaneous health and disease
  • Ageing pathways and stress biology using alternative models
  • Translational screening of natural products and nutraceuticals
  • Evidence-based evaluation of Ayurvedic formulations
  • Integrative regenerative medicine and systems biology